Organic Acids Test (OAT) by Mosaic Diagnostics

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A Nutritional and Metabolic Snapshot

Organic acids are products of the body’s metabolic pathways. Evaluation of these downstream metabolites from various metabolic pathways provides insight into important areas related to gut health, mitochondrial dysfunction, neurotransmitter status, indicators of detoxification and macronutrient breakdown and nutritional status. This makes organic acid testing a valuable tool to assess the functional need for essential nutrients, diet modification, antioxidant protection, detoxification, and other therapies.

The Organic Acids Test (OAT) provides a comprehensive nutritional and metabolic snapshot of an individual’s overall health. The OAT measures 76 organic acids from one easy to collect urine sample.

Why Run an Organic Acids Test (OAT)?

The Organic Acids Test (OAT) is a simple and efficient way to assess a number of metabolic pathways providing insight into imbalances and nutrient needs. The OAT can provide insight into a wide range of conditions, making it valuable for individuals who are experiencing complex chronic conditions.

 

The OAT test report is organized into clinically useful categories including:

  • Intestinal Microbial Overgrowth markers evaluate for candida activity, clostridia bacteria toxins, potential mold exposure, and imbalance in the gut microflora.
  • Oxalate Metabolites provide insight into oxalate levels being generated by organisms within the system or via dietary contributions.
  • Glycolytic Cycle Metabolites and Mitochondrial Markers (Krebs Cycle and Amino Acid Metabolites) evaluate for metabolic efficiency (e.g., use of glucose and amino acids for energy generation) and mitochondrial dysfunction.
  • Neurotransmitter Metabolites evaluate for phenylalanine, tyrosine and tryptophan metabolism which are linked to neurotransmitter status and quinolinic acid production.
  • Pyrimidine Metabolites & Ketone and Fatty Acid Oxidation markers give insight into folate status and cellular turnover, as well as mitochondrial utilization of fatty acids for energy production.
  • Nutritional Markers provide insight into the sufficiency of essential vitamins, antioxidants, and metabolic pathway co-factors.
  • Indicators of Detoxification assess for the presence of oxidative stress via markers of glutathione sufficiency and methylation versus transsulfuration function.
  • Amino Acid Metabolites may suggest functional nutrient need or be reflective of genetic metabolic dysfunction if a consistently, persistently elevated level of a particular analyte is noted.
  • The Mineral Metabolism marker provides insight into dietary intake of phosphate and can give insights into Vitamin D levels.

ANALYTES

The OAT measures 76 organic acids from one easy to collect urine sample. See full list of markers below:

  • Citramalic Acid
  • 5-Hydroxymethyl-2-furoic Acid
  • 3-Oxoglutaric Acid
  • Furan-2,5-dicarboxylic Acid
  • Furancarbonylglycine
  • Tartaric Acid
  • Arabinose
  • Carboxycitric Acid
  • Tricarballylic Acid
  • 2-Hydroxyphenylacetic Acid
  • 4-Hydroxyphenylacetic Acid
  • 4-Hydroxybenzoic Acid
  • 4-Hydroxyhippuric Acid
  • Hippuric Acid
  • 3-Indoleacetic Acid
  • Succinic Acid
  • HPHPA (Clostridia marker)
  • 4-Cresol (C. difficile)
  • DHPPA (beneficial bacteria)
  • Glyceric Acid
  • Glycolic Acid
  • Oxalic Acid
  • Lactic Acid
  • Pyruvic Acid
  • 2-Hydroxybutyric Acid
  • Fumaric Acid
  • Malic Acid
  • 2-Oxoglutaric Acid
  • Aconitic Acid
  • Citric Acid
  • Homovanillic Acid (HVA)
  • Vanillmandelic Acid (VMA)
  • HVA/VMA Ratio
  • 5-Hydroxyindoleacetic Acid (5-HIAA)
  • Quinolinic Acid
  • Kynurenic Acid
  • HVA/DOPAC Ratio
  • Dihydroxyphenylacetic (DOPAC)
  • Uracil
  • Thymine
  • 3-Hydroxybutyric Acid
  • Acetoacetic Acid
  • 4-Hydroxybutyric Acid
  • Ethylmalonic Acid
  • Methylsuccinic Acid
  • Adipic Acid
  • Suberic Acid
  • Sebacic Acid
  • Methylmalonic Acid (Vitamin B12)
  • Pyridoxic Acid (Vitamin B6)
  • Pantothenic Acid (Vitamin B5)
  • Glutaric Acid (Vitamin B2-Riboflavin)
  • Ascorbic Acid (Vitamin C)
  • 3-OH-3-Methylglutaric Acid (Vitamin Q10/CoQ10)
  • N-Acetylcysteine (Glutathione precursor and chelating agent)
  • Methylcitric Acid (Vitamin H-Biotin)
  • Pyroglutamic Acid
  • Orotic Acid
  • 2-Hydroxyhippuric Acid
  • 2-Hydroxyisovaleric Acid
  • 2-Oxoisovaleric Acid
  • 3-Methyl-2-oxovaleric Acid
  • 2-Hydroxyisocaproic Acid
  • 2-Oxoisocaproic Acid
  • 2-Oxo-4-methiolbutyric Acid
  • Mandelic Acid
  • Phenyllactic Acid
  • Phenylpyruvic Acid
  • Homogentisic Acid
  • 4-Hydroxyphenyllactic Acid
  • N-Acetylaspartic Acid
  • Malonic Acid
  • 3-Methylglutaric Acid
  • 3-Hydroxyglutaric Acid
  • 3-Methylglutaconic Acid
  • Phosphoric Acid

SAMPLE REPORTS

The OAT test report is organized into seven clinically useful categories including:

  • Intestinal Microbial Overgrowth – Evaluates for invasive candida, clostridia bacteria toxins, potential mold exposure, and imbalance in the gut microflora
  • Glycolytic and Mitochondrial Metabolites – Evaluates for mitochondrial dysfunction
  • Neurotransmitter Metabolites – Evaluates for phenylalanine, tyrosine and tryptophan metabolism linked to neurotransmitter status and quinolinic acid production
  • Pyrimidines and Fatty Acids – Evaluates for folate metabolism, as well as fatty acid metabolism problems which can contribute to mitochondrial dysfunction
  • Oxalates
  • Nutritional Markers
  • Amino Acids
  • Body’s Capacity to Detoxify

DOWNLOAD - Organic Acids Test (OAT) Sample Test Report (Sample Report)

 

DOWNLOAD - Clinical Significance of the Organic Acids Test Brochure (Sample Report)

NUTRITIONIST FORMULATED, DESIGNED TO PERFORM

At the core of helping you achieve your goals is our nutritionist that constantly researches the most cutting edge ingredients. Ingredients are important, but they need to be combined in the correct ratios and dosages to be effective and that’s exactly how Yuda product is created.

*These statements have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure, or prevent any disease.

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